Abstract
In both developed and undeveloped nations, chronic liver illness is a fatal ailment that has a significant impact on morbidity and mortality rates. The existing healthcare system does not have any hepatoprotective drugs that are considered to be of the highest quality, which limits its ability to treat or prevent liver illnesses successfully. Because of this, it has become vital to count on complementary and alternative medical techniques in order to treat liver illnesses and diseases. Zingiber officinale Roscoe or ginger is one of the spices that is consumed on a regular basis and is without a doubt one of the most common spices. In addition to its application in culinary settings, ginger was used in a wide range of traditional and folk medical systems to treat both acute and chronic conditions. It is also claimed to be beneficial to one’s health in a number of ways. Recent preclinical studies suggested the hepatoprotective properties of ginger and for protecting the body against a wide array of xenobiotic and inorganic substances. Ginger has also shown to defend the body against heavy metals. According to mechanistic studies, the protective benefits are exerted by the production of antioxidants, the scavenging of free radicals, the promotion of cytoprotection, and the modification of the levels of detoxifying enzymes. This chapter emphasizes the areas that require additional exploration to demonstrate ginger’s activity and usefulness as a multifaceted hepatoprotective agent. It also highlights the discoveries linked to ginger’s beneficial qualities in lessening the deleterious effects of hepatotoxins.
Reference Series in Phytochemistry